General information:
| Function | ATP-binding cassette protein subfamily G; member 2; putative (ABCG2) |
| Gene type | Protein coding gene |
| Transcript location | chr.06:37372-42353|- |
| Alternative SL | 42434(7),42343(4),42238(1),42447(1) |
| Alternative polyA site | 37377(1) |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.06.T0090 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.06.0090 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0016020,GO:0000166,GO:0005524,GO:0016887,GO:0017111,GO:0042626
Associated PubMed publications:
- Perea A, Manzano JI, Castanys S, Gamarro F. 2016. The LABCG2 Transporter from the Protozoan Parasite Leishmania Is Involved in Antimony Resistance. Antimicrob Agents Chemother 60: 3489-3496. [PUBMED]
- Campos-Salinas J, Leon-Guerrero D, Gonzalez-Rey E, Delgado M, Castanys S, Perez-Victoria JM, Gamarro F. 2013. LABCG2, a new ABC transporter implicated in phosphatidylserine exposure, is involved in the infectivity and pathogenicity of Leishmania. PLoS neglected tropical diseases 7: e2179. [PUBMED]
- Manzano JI, Perea A, Leon-Guerrero D, Campos-Salinas J, Piacenza L, Castanys S, Gamarro F. 2017. Leishmania LABCG1 and LABCG2 transporters are involved in virulence and oxidative stress: functional linkage with autophagy. Parasites & vectors 10: 267. [PUBMED]
- Perea A, Manzano JI, Kimura Y, Ueda K, Castanys S, Gamarro F. 2018. Leishmania LABCG2 transporter is involved in ATP-dependent transport of thiols. Biochem J 475: 87-97. [PUBMED]