General information:
| Function | signal peptidase type I; putative |
| Gene type | Protein coding gene |
| Transcript location | chr.08:185745-186873|+ |
| Alternative SL | 185875(2),185304(2),185826(1) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.08.T0450 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.08.0450 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0006508,GO:0008233,GO:0006465,GO:0016020
Associated PubMed publications:
- Rafati S, Salmanian AH, Taheri T, Masina S, Schaff C, Taslimi Y, Fasel N. 2004. Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis. Mol Biochem Parasitol 135: 13-20. [PUBMED]
- Taheri T, Salmanian AH, Gholami E, Doustdari F, Zahedifard F, Rafati S. 2010. Leishmania major: disruption of signal peptidase type I and its consequences on survival, growth and infectivity. Exp Parasitol 126: 135-145. [PUBMED]