General information:
| Function | mitochondrial DNA polymerase beta |
| Gene type | Protein coding gene |
| Transcript location | chr.08:400165-402719|- |
| Alternative SL | 402724(2),402716(5),402636(4),402931(3),402692(1) |
| Alternative polyA site | 400181(1) |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.08.T0890 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.08.0890 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0003677,GO:0003887,GO:0003824,GO:0006281,GO:0006260,GO:0016779
Associated PubMed publications:
- Ramiro MJ, Hanke T, Taladriz S, Larraga V. 2002. DNA polymerase beta mRNA determination by relative quantitative RT-PCR from Leishmania infantum intracellular amastigotes. Parasitol Res 88: 760-767. [PUBMED]
- Alonso A, Terrados G, Picher AJ, Giraldo R, Blanco L, Larraga V. 2006. An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair. DNA Repair (Amst) 5: 89-101. [PUBMED]
- Taladriz S, Hanke T, Ramiro MJ, Garcia-Diaz M, Garcia De Lacoba M, Blanco L, Larraga V. 2001. Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation. Nucleic Acids Res 29: 3822-3834. [PUBMED]
- Mejia E, Burak M, Alonso A, Larraga V, Kunkel TA, Bebenek K, Garcia-Diaz M. 2014. Structures of the Leishmania infantum polymerase beta. DNA Repair (Amst) 18: 1-9. [PUBMED]