General information:
| Function | guanosine diphosphatase; putative |
| Gene type | Protein coding gene |
| Transcript location | chr.10:73847-77168|+ |
| Alternative SL | 73837(1) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
-
Here you can download sequence data derived from our research.
- LmjF.10.T0170 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.10.0170 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0016787
Associated PubMed publications:
- Bastos MS, Tremblay A, Agripino JM, Rabelo ILA, Barreto LP, Pelletier J, Lecka J, Silva-Junior A, Bressan GC, Almeida MR et al. 2017. The expression of NTPDase1 and -2 of Leishmania infantum chagasi in bacterial and mammalian cells: Comparative expression, refolding and nucleotidase characterization. Protein Expr Purif 131: 60-69. [PUBMED]
- Sansom FM, Ralton JE, Sernee MF, Cohen AM, Hooker DJ, Hartland EL, Naderer T, McConville MJ. 2014. Golgi-located NTPDase1 of Leishmania major is required for lipophosphoglycan elongation and normal lesion development whereas secreted NTPDase2 is dispensable for virulence. PLoS neglected tropical diseases 8: e3402. [PUBMED]